Engram neurons: Encoding, consolidation, retrieval, and forgetting of memory | Molecular Psychiatry

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Advertisement Molecular Psychiatry volume  28,  pages 3207–3219 (2023)Cite this article 9401 Accesses 2 Citations 11 Altmetric Metrics details Tremendous strides have been made in our understanding of the neurobiological substrates of memory – the so-called memory “engram”. Here, we integrate recent progress in the engram field to illustrate how engram neurons transform across the “lifespan” of a memory — from initial memory encoding, to consolidation and retrieval, and ultimately to forgetting. To do so, we first describe how cell-intrinsic properties shape the initial emergence of the engram at memory encoding. Second,

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• Yusha Dulkina